Metergoline, FI-6337, Liserdol
甲麦角林Chemical Name: (+)-(1,6-Dimethylergoline-8beta-ylmethyl)carbamic acid benzyl ester
CAS No. 17692-51-2
项目整合开发状态: Launched-1987
项目研究机构: Pfizer (Originator), Wyeth Pharmaceuticals (Not Determined)
合成路线:Reduction of 1-methyl-dihydro-D-lisergamide (I) by means of LiAlH4 afforded the corresponding amine (II).Subsequent acylation of amine (II) with benzyl chloroformate provided the title benzyl carbamate.
📌 参考资料/链接：
参考文献标题:6-Methyl- and 1,6-dimethyl-8beta-carbobenzyloxy-aminomethyl-10alpha-ergoline as inhibitors of prolactin secretion
文献作者:di Salle,E.; Praga,C.; Castegnaro,E.
参考来源:US 4151283