Penbutolol sulfate, Hoe-893d, Hoe-39893d, Levatol, Betapressin
甲醇中喷布特罗溶液标准物质 喷布洛尔 Chemical Name: (S)-1-(2-Cyclopentylphenoxy)-3-(1,1-dimethylethylamino)-2-propanol sulfate (2:1)
CAS No. 38363-32-5, 38363-40-5 (free base)
项目整合开发状态: Launched-1981
项目研究机构: Aventis Behring (Originator), Aventis Pharma (Originator)
合成路线:The reaction of 2-cyclopentylphenol (I) with epichlorhydrin (II) in a basic medium yields 1,2-epoxy-3-(2'-cyclopentylphenoxy)propane (III),which is the condensed with tert-butylamine (IV) in hot ethanol.
📌 参考资料/链接：
参考文献标题:
文献作者:Ruschig,H.; et al.
参考来源:ZA 6807915
📄 详细内容
合成路线:The reaction of 2-cyclopentylphenol (I) with epichlorhydrin (II) in a basic medium yields 1,2-epoxy-3-(2'-cyclopentylphenoxy)propane (III),which is the condensed with tert-butylamine (IV) in hot ethanol.
参考文献标题:Penbutolol
文献作者:Castar,J.; Weetman,D.F.
参考来源:Drugs Fut 1976,1(10),494
产品链接: CAS No. 38363-32-5›› 产品链接: CAS No.38363-40-5››