合成路线:This compound can be prepared by two different ways:1) The Grignard reaction of 3-oximino-17-oxoestre-4,9,11-triene (I) with allylmagnesium bromide (II) in ether - benzene gives 3-oximino-17alpha-allyl-17-hydroxyestra-4,9,11-triene (III),which pyruvic acid - acetic acid .2) The dehydration of 17alpha-allyl-11beta,17beta-dihydroxyestra-4,9-dien-3-one (IV) eith refluxing aqueous 60% formic acid.
参考文献标题:
文献作者:Bertin,D.; Pierdet,A.
参考来源:DE 1618810; FR 1503984; GB 1128787; NL 6702462
合成路线:This compound can be prepared by two different ways:1) The Grignard reaction of 3-oximino-17-oxoestre-4,9,11-triene (I) with allylmagnesium bromide (II) in ether - benzene gives 3-oximino-17alpha-allyl-17-hydroxyestra-4,9,11-triene (III),which pyruvic acid - acetic acid .2) The dehydration of 17alpha-allyl-11beta,17beta-dihydroxyestra-4,9-dien-3-one (IV) eith refluxing aqueous 60% formic acid.
参考文献标题:Altrenogest
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; Bogan,J.A.
参考来源:Drugs Fut 1892,7(10),711
产品链接: CAS No. 850-52-2››