Broperamole, TR-2378
溴哌莫Chemical Name: 1-[3-[5-(3-Bromophenyl)-2H-tetrazol-2-yl]propionyl]piperidine
CAS No. 33144-79-5
项目整合开发状态: Biological Testing
项目研究机构:
合成路线:The chlorination of 3-[5-(m-bromophenyl)-2H-tetrazol-2-yl]propionic acid (I) with thionyl chloride in refluxing chloroform gives the corresponding acyl chloride (II),which is then treated with dry piperidine (III) in THF
📌 参考资料/链接：
参考文献标题:Broperamole
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; Arrigoni,Martelli,E.
参考来源:Drugs Fut 1981,6(4),214
📄 详细内容
合成路线:The chlorination of 3-[5-(m-bromophenyl)-2H-tetrazol-2-yl]propionic acid (I) with thionyl chloride in refluxing chloroform gives the corresponding acyl chloride (II),which is then treated with dry piperidine (III) in THF
参考文献标题:
文献作者:
参考来源:CA 950908; DE 2063173; FR 2081397; GB 1319357; GB 1320140; JP 7141904; US 3681336
产品链接: CAS No. 33144-79-5››