合成路线:By reaction of bleomycinic acid copper salt (I) with N-[(S)-1'-phenylethyl]-1,3-diaminopropane (II) by means of carbodiimides,or by means of 6-chloro-1-(p-chlorobenzenesulfonyloxy)benzotriazole in DMF.
参考文献标题:Novel process for producing antibiotics bleomycin
文献作者:Umezawa,H.; et al.
参考来源:CA 923534; FR 2034552; GB 1292081; US 3846400
合成路线:By reaction of bleomycinic acid copper salt (I) with N-[(S)-1'-phenylethyl]-1,3-diaminopropane (II) by means of carbodiimides,or by means of 6-chloro-1-(p-chlorobenzenesulfonyloxy)benzotriazole in DMF.
参考文献标题:Preparation of 3-[(S)-1'-phenylethylamino]-propylamino-bleomycin
文献作者:Kunishima,A.; et al.
参考来源:JP 54041387
合成路线:By reaction of bleomycinic acid copper salt (I) with N-[(S)-1'-phenylethyl]-1,3-diaminopropane (II) by means of carbodiimides,or by means of 6-chloro-1-(p-chlorobenzenesulfonyloxy)benzotriazole in DMF.
参考文献标题:3-[(S)-1'-Phenylethylamino]propylaminobleomycin,non-toxic salt thereof,and method for producing same
文献作者:Takita,T.; et al.
参考来源:FR 2396021; GB 2001962; US 4195018; US 4238391
产品链接: CAS No. 68247-85-8›› 产品链接: CAS No.70384-29-1››