Tiobutarit, Bucillamine, DE-019, SA-96, Rimatil
布西拉明Chemical Name: N-(2-Mercapto-2-methylpropionyl)-L-cysteine
CAS No. 65002-17-7
项目整合开发状态: Launched-1987
项目研究机构: Santen (Originator)
合成路线:The condensation of 2-benzylmercaptoisobutyryl chloride (I) with S-benzyl-L-cysteine (II) by means of NaOH in water gives N-(2-benzylmercaptoisobutyryl)-S-benzyl-L-cysteine (III),which is treated with Na in liquid ammonia.
📌 参考资料/链接：
参考文献标题:Cysteine derivatives
文献作者:Fujita,T.; et al.(Santen Pharmaceutical Co.,Ltd.)
参考来源:DE 2709820; FR 2344533; GB 1530071; JP 53005112; US 4137420; US 4305958
📄 详细内容
合成路线:The condensation of 2-benzylmercaptoisobutyryl chloride (I) with S-benzyl-L-cysteine (II) by means of NaOH in water gives N-(2-benzylmercaptoisobutyryl)-S-benzyl-L-cysteine (III),which is treated with Na in liquid ammonia.
参考文献标题:SA-96
文献作者:Castar,J.; Arrigoni-Martelli,E.; Blancafort,P.; Serradell,M.N.
参考来源:Drugs Fut 1981,6(5),292
产品链接: CAS No. 65002-17-7››