Nonachlazine, Azaclorzine, AY-25239(hydrochloride)
氮氯嗪Chemical Name: 2-Chloro-10-[3-(hexahydropyrrolo[1,2-a]pyrazin-2[1H]-yl)propionyl]-phenothiazine; 2'-Chloro-10'-[beta-N-(1,4-diazabicyclo-[4,3-0]-propionyl]phenothiazine
CAS No. 49864-70-2, 49780-10-1 (HCl)
项目整合开发状态: Biological Testing
项目研究机构: Russian Academy of Medical Sciences (Originator)
合成路线:By condensation of 2-chloro-10-(beta-chloropropionyl)phenothiazine (I) with 1,4-diazabicylo[4.3.0]nonane (II) in refluxing toluene.
📌 参考资料/链接：
参考文献标题:Azaclorzine
文献作者:Blancafort,P.; Castar,J.
参考来源:Drugs Fut 1976,1(4),157
📄 详细内容
合成路线:By condensation of 2-chloro-10-(beta-chloropropionyl)phenothiazine (I) with 1,4-diazabicylo[4.3.0]nonane (II) in refluxing toluene.
参考文献标题:10'-(Omega-N-1,4-Diazabyzyklo-4,m,O-alkanylacyl)phenothiazine,ihre S鋟readditionssalze und ihre quatern鋜en Salze,Verfahren zu ihrer Herstellung und ihre Andwendung
文献作者:Likhosherstov,A.M.; et al.
参考来源:DE 2210382
合成路线:By condensation of 2-chloro-10-(beta-chloropropionyl)phenothiazine (I) with 1,4-diazabicylo[4.3.0]nonane (II) in refluxing toluene.
参考文献标题:pharmacology of the new anti-anginal frug nonachlazine
文献作者:Markova,G.A.; Kaverina,N.V.
参考来源:Farmakol Toksikol 1975,38(2),173
产品链接: CAS No. 49864-70-2›› 产品链接: CAS No.49780-10-1››