Fluperlapine, NB-106689
氟扑来平Chemical Name: 3-Fluoro-6-(4-methyl-1-piperazinyl)-11H-dibenz[b,e]azepine; 3-Fluoro-6-(4-methyl-1-piperazinyl)morphanthridine
CAS No. 67121-76-0
项目整合开发状态: Biological Testing
项目研究机构: Novartis (Originator)
合成路线:By condensation of 3-fluoro-5,6-dihydromorphanthridin-6-one (I) with N-methylpiperazine (II) by means of POCl3 and N,N-dimethylaniline.
📌 参考资料/链接：
参考文献标题:Fluperlapine
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1984,9(5),326
📄 详细内容
合成路线:By condensation of 3-fluoro-5,6-dihydromorphanthridin-6-one (I) with N-methylpiperazine (II) by means of POCl3 and N,N-dimethylaniline.
参考文献标题:3-Fluor-morphanthridine,ihre Herstellung und Verwengung
文献作者:Hunziker,F.; Fischer,R.
参考来源:DE 2803542
合成路线:By condensation of 3-fluoro-5,6-dihydromorphanthridin-6-one (I) with N-methylpiperazine (II) by means of POCl3 and N,N-dimethylaniline.
参考文献标题:Morphanthridine derivatives
文献作者:Hunziker,F.; Fischer,R.
参考来源:DE 2748920; FR 2370745; GB 1592329; GB 1592330; JP 53059686; US 4308207
产品链接: CAS No. 67121-76-0››