Binifibrato, Binifibrate, WAC-104, Antopal retard, Biniwas
比尼贝特Chemical Name: 2-(4-Chlorophenoxy)-2-methylpropionic acid 1,3-bis(pyridin-3-ylcarbonyloxy)propan-2-ol ester
CAS No. 69047-39-8
项目整合开发状态: Launched-1987
项目研究机构: Soc. Esp. Esp. Farmaco-Terap閡ticas (Originator), Wassermann (Originator)
合成路线:Sterification of 1,3-dichloro-2-propanol (I) with p-chlorophenoxyisobutyric acid (II) forms 1,3-dichloro-2-propanol 2-p-chlorophenoxyisobutirate (III),which,by reaction with the sodium salt of nicotinic acid,is transformed into trihydroxipropane 2-p-chlorophenoxyisobutyrate-1,3-dinicotinate.
📌 参考资料/链接：
参考文献标题:WAC-104
文献作者:Castar,J.
参考来源:Drugs Fut 1979,4(9),681
📄 详细内容
合成路线:Sterification of 1,3-dichloro-2-propanol (I) with p-chlorophenoxyisobutyric acid (II) forms 1,3-dichloro-2-propanol 2-p-chlorophenoxyisobutirate (III),which,by reaction with the sodium salt of nicotinic acid,is transformed into trihydroxipropane 2-p-chlorophenoxyisobutyrate-1,3-dinicotinate.
参考文献标题:Procedimiento para la obtenci髇 de un 閠er mixto sim閠rico del 1,2,3-trihidroxipropano
文献作者:Andreoli,R.; Cirera,X.(Sociedad Espa駉la de Especialidades Farmaco-Terap閡ticas SA)
参考来源:ES 463218
产品链接: CAS No. 69047-39-8››