Bulaquine, 80/53, CDRI-80/53
布拉喹Chemical Name: N1-(3-Acetyl-4,5-dihydrofuran-2-yl)-N4-(6-methoxyquinolin-8-yl)pentane-1,4-diamine; 1-[4,5-Dihydro-2-[4-(6-methoxyquinolin-8-ylamino)pentylamino]furan-3-yl]ethanone
CAS No. 79781-00-3
项目整合开发状态: Launched-2000
项目研究机构: Central Drug Research Institute (Originator), Nicholas Piramal (Codevelopment)
合成路线:The title enamine derivative was prepared by condensation of primaquine (I) with acetyl butyrolactone (II) in the presence of piperidine.
📌 参考资料/链接：
参考文献标题:Use of primaquine derivs.for the treatment of malaria
文献作者:Bhaduri,A.P.; Singh,S.; Singh,S.K.; Asthana,O.P.; Pratap,R.; Gupta,R.C.; Srivastava,S.; Thapliyal,H.P.; Puri,S.K.; Dutta,G.P.; Dwivedi,A.K.; Srivastava,P.; Pandey,V.C.; Srivastava,J.S.(Council of Scientific and Industrial Research)
参考来源:EP 1055427