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项目整合精选>>>Budesonide, S-1320, Pulmaxan, Pulmicort, Rhinocort, Entocort, Budenofalk, Preferid, Pulmicort turbuhaler, Budiair, Pulmaxan turbohaler, Pulmicort Topinasal, Pulmicort Respules, Inflammide, Giona Easyhaler, Miflonide, Rhinocort Aqua
Budesonide, S-1320, Pulmaxan, Pulmicort, Rhinocort, Entocort, Budenofalk, Preferid, Pulmicort turbuhaler, Budiair, Pulmaxan turbohaler, Pulmicort Topinasal, Pulmicort Respules, Inflammide, Giona Easyhaler, Miflonide, Rhinocort Aqua
布地奈德Chemical Name: 16alpha,17alpha-(22R,S)-Propylmethylenedioxypregna-1,4-diene-11beta,21-diol-3,20-dione; (11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
CAS No. 51333-22-3
项目整合开发状态: Launched-1981
项目研究机构: AstraZeneca (Originator), Boehringer Ingelheim (Not Determined), Eisai (Marketer), Chiesi (Formulation), CyDex (Formulation), MAP Pharmaceuticals (Formulation), ML Laboratories (Formulation), Orion Corp. (Formulation), Sheffield (Formulation), SkyePharma
合成路线:From 16alpha-hydroxyprednisolone (III) and n-butyraldehyde (A) in the presence of an acid catalyst.Budesonide is defined as a 1:1 mixture of the two epimers (I) and (II).
📌 参考资料/链接：
参考文献标题:Budesonide
文献作者:Dharma,A.P.
参考来源:Drugs Fut 1980,5(4),179
📄 详细内容
合成路线:From 16alpha-hydroxyprednisolone (III) and n-butyraldehyde (A) in the presence of an acid catalyst.Budesonide is defined as a 1:1 mixture of the two epimers (I) and (II).
参考文献标题:Synthesis and antiinflammatory properties of budesonide,a new nonhalogenated glucocorticoid with high local activity
文献作者:Thal閚,A.; Brattsand,R.
参考来源:Arzneim-Forsch Drug Res 1979,29(11),1687-90
产品链接: CAS No. 51333-22-3››