Piflutixol
哌氟替索Chemical Name: 2-[1-[3(Z)-[7-Fluoro-2-(trifluoromethyl)-10H-dibenzo[b,e]thiopyran-10-ylidene]propyl]piperidin-4-yl]ethanol
CAS No. 54341-02-5
项目整合开发状态: Not Determined
项目研究机构:
合成路线:The Grignard reaction of 2-trifluoromethyl-6-fluorothioxanthone (I) with allylmagnesium bromide (II) in ether gives 2-trifluoromethyl-6-fluoro-9-(2-propenylidene)thioxanthene (III),which is then condensed with 4-(2-hydroxyethyl)piperidine (IV) at 90 C.
📌 参考资料/链接：
参考文献标题:
文献作者:Buus,J.M.L.; et al.
参考来源:DE 2631389
📄 详细内容
合成路线:The Grignard reaction of 2-trifluoromethyl-6-fluorothioxanthone (I) with allylmagnesium bromide (II) in ether gives 2-trifluoromethyl-6-fluoro-9-(2-propenylidene)thioxanthene (III),which is then condensed with 4-(2-hydroxyethyl)piperidine (IV) at 90 C.
参考文献标题:Piflutixol
文献作者:Castar,J.; Owen,R.T.
参考来源:Drugs Fut 1978,3(9),670
产品链接: CAS No. 54341-02-5››