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Gemfibrozil, GEM, CI-719, Gevilon, Lipur, Lipozid, Innogem, Lopid

吉非罗齐Chemical Name: 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid; 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid
CAS No. 25812-30-0
项目整合开发状态: Launched-1982
项目研究机构: Pfizer (Originator), Egis (Not Determined), Pfizer (Not Determined), Abbott (Licensee), Sankyo (Licensee)
合成路线:The sodium isobutyrate (I) is metallated with lithium diisopropylamide,and the resulting compound is alkylated with 3-(2,5-dimethylphenoxy)propyl bromide.
📌 参考资料/链接:
参考文献标题:Gemfibrozil
文献作者:Sungurbey,K.; Castar,J.
参考来源:Drugs Fut 1976,1(11),520

📄 详细内容


合成路线:The sodium isobutyrate (I) is metallated with lithium diisopropylamide,and the resulting compound is alkylated with 3-(2,5-dimethylphenoxy)propyl bromide.
参考文献标题:2,2-Dimethyl-omega-aryloxyalkans鋟ren und ihre Salze und Ester
文献作者:Creger,P.L.
参考来源:DE 1925423; FR 2008997; GB 1225575


产品链接: CAS No. 25812-30-0››