合成路线:By reaction of sodium phenobarbital (I) with 2 mols of methyl chloromethyl ether (A) in DMF.It can also be obtained by reaction of phenobarbital (II),2 mols of NaH,LiH,KH,LiOH or t-BuOK and 2 moles of methyl chloromethyl ether (A) in DMF.
参考文献标题:Verfahren zur Herstellung von 5,5-disubstituierten N,N'-Dialkyloxyalkyl- oder N,N'-Dibenzyloxyalkylverbindugen der Barbitus鋟re
文献作者:Vida,J.A.(The Kendall Company)
参考来源:DE 2005108; FR 2033950; GB 1276387
合成路线:By reaction of sodium phenobarbital (I) with 2 mols of methyl chloromethyl ether (A) in DMF.It can also be obtained by reaction of phenobarbital (II),2 mols of NaH,LiH,KH,LiOH or t-BuOK and 2 moles of methyl chloromethyl ether (A) in DMF.
参考文献标题:Eterobarb
文献作者:Castar,J.; Playle,A.C.
参考来源:Drugs Fut 1976,1(6),286
合成路线:By reaction of sodium phenobarbital (I) with 2 mols of methyl chloromethyl ether (A) in DMF.It can also be obtained by reaction of phenobarbital (II),2 mols of NaH,LiH,KH,LiOH or t-BuOK and 2 moles of methyl chloromethyl ether (A) in DMF.
参考文献标题:Anticonvulsants.1.Alkoxymethyl derivatives of barbiturates and diphenylhydantoin
文献作者:Samour,C.M.; et al.
参考来源:J Med Chem 1971,14(3),187
产品链接: CAS No. 27511-99-5››