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项目整合精选>>>Etodolic acid, Etodolac, RAK-591, AY-24236, Lodine SR, Lodine XL, Osteluc, Hypen, Edolan, Ultradol, Lodine
Etodolic acid, Etodolac, RAK-591, AY-24236, Lodine SR, Lodine XL, Osteluc, Hypen, Edolan, Ultradol, Lodine
依托度酸Chemical Name: 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
CAS No. 41340-25-4
项目整合开发状态: Launched-1985
项目研究机构: Shire Pharmaceuticals (Proprietary), Wyeth Pharmaceuticals (Originator), Nippon Shinyaku (Licensee)
合成路线:By condensation of 3-(2-hydroxyethyl)-8-ethylindole (I) with ethyl 3-oxopentanoate (II) in benzene by means of p-toluenesulfonic acid.
📌 参考资料/链接：
参考文献标题:Etodolic acid
文献作者:Castar,J.; Arrigoni-Martelli,E.
参考来源:Drugs Fut 1977,2(1),21
📄 详细内容
合成路线:By condensation of 3-(2-hydroxyethyl)-8-ethylindole (I) with ethyl 3-oxopentanoate (II) in benzene by means of p-toluenesulfonic acid.
参考文献标题:1-Carboxamido pyrano(thiopyrano) [3,4-6]indole derivatives
文献作者:Demerson,C.A.; et al.
参考来源:DE 2226340; FR 2140154; GB 1391005; US 3843681
产品链接: CAS No. 41340-25-4››