BMS-181174, BMY-25067
N-7-(2-(硝基苯基二硫)乙基)丝裂霉素 CChemical Name: [1aS-(1aalpha,8beta,8aalpha,8balpha)]-8-(Carbamoyloxymethyl)-8a-methoxy-5-methyl-6-[2-(4-nitrophenyldisulfanyl)ethylamino]-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
CAS No. 95056-36-3
项目整合开发状态: Phase II
项目研究机构: Bristol-Myers Squibb (Originator)
合成路线:By condensation of mitomycin A (I) with 2-(4-nitrophenyldithio)ethylamine (II) by means of triethylamine in methanol.
📌 参考资料/链接:
参考文献标题:Pyrroloindole derivs
文献作者:Vyas,D.M.; Doyle,T.W.; Chiang,Y.(Bristol-Myers Squibb Co.)
参考来源:BE 0899380; CH 661273; ES 8602798; FR 2543953; GB 2140799; JP 1984205382
📄 详细内容
合成路线:By condensation of mitomycin A (I) with 2-(4-nitrophenyldithio)ethylamine (II) by means of triethylamine in methanol.
参考文献标题:BMS-181174
文献作者:Robinson,C.O.; Robinson,K.; Castar,J.
参考来源:Drugs Fut 1996,21(10),999
产品链接: CAS No. 95056-36-3››