MCI-154
N-(2-氯乙基)丁酰胺Chemical Name: 6-[4-(4-Pyridylamino)phenyl]-2,3,4,5-tetrahydropyridazin-3-one hydrochloride
CAS No. 98326-33-1
项目整合开发状态: Phase II
项目研究机构: Mitsubishi Pharma (Originator)
合成路线:By condensation of 6-(4aminophenyl)2,3,4,5-tetrahydropyridazin-3-one (I) with 4-bromopyridine (II) in hot DMF,followed by extraction of the free base with Na2CO3 and treatment with ethanolic HCl.
📌 参考资料/链接：
参考文献标题:6-(p-Heterocyclylaminophenyl)pyridazin-3-one derivs.
文献作者:Kobayashi,M.; Narimatsu,A.; Furuya,R.; Shimooda,I.; Kitada,Y.; Okushima,H.(Mitsubishi Chemical Corp.)
参考来源:EP 0145019; JP 1985126282; JP 1985197672; US 4661484; US 4971968
📄 详细内容
合成路线:By condensation of 6-(4aminophenyl)2,3,4,5-tetrahydropyridazin-3-one (I) with 4-bromopyridine (II) in hot DMF,followed by extraction of the free base with Na2CO3 and treatment with ethanolic HCl.
参考文献标题:MCI-154
文献作者:Castar,R.M.; Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1987,12(9),856
产品链接: CAS No. 98326-33-1››