NZ-419
5-羟基-1-甲基咪唑烷-2,4-二酮Chemical Name: 5-Hydroxy-1-methylhydantoin; 5-Hydroxy-1-methylimidazolidine-2,4-dione
CAS No. 84210-26-4
项目整合开发状态: Phase II
项目研究机构: Nippon Zoki (Originator)
合成路线:By cyclization of glyoxylic acid butyl ester (I) with N-methylurea in refluxing acetic acid/water.
📌 参考资料/链接：
参考文献标题:Hydantoin derivs.and pharmaceutical compsns.containing them
文献作者:Ienaga,K.; Nakamura,K.(Nippon Zoki Pharmaceutical Co.,Ltd.)
参考来源:AU 8539172; EP 0160618; ES 8609272; JP 1986122275; US 4647574