Picotamide, G-137, Plactidil
4-甲氧基-N,N'-二(3-吡啶甲基)-1,3-苯二甲酰胺Chemical Name: N,N'-Bis(3-picolyl)-4-methoxyisophthalamide; 4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide
CAS No. 32828-81-2
项目整合开发状态: Launched-1987
项目研究机构: Samil (Originator)
合成路线:By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.
📌 参考资料/链接：
参考文献标题:Inhibitor of blood plate aggregation
文献作者:Orzalesi,G.; Selleri,T.(L.Manetti & Roberts SpA)
参考来源:US 3973026
📄 详细内容
合成路线:By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.
参考文献标题:Picotamide
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; Hopkins,S.J.
参考来源:Drugs Fut 1980,5(1),37
合成路线:By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.
参考文献标题:Picolylamides de l'acide 4-hydroxy-isophalique,leurs d閞iv閟 m閠hoxyl?et 閠hoxyl?et leur proc閐?de fabrication
文献作者:Orzalesi,G.; Selleri,T.
参考来源:BE 0851967; FR 2100850
合成路线:By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.
参考文献标题:New 4-hydroxyisophatlic acid derivatives having anticoagulant and fibrinolytic activity
文献作者:Selleri,R.; et al.
参考来源:Chimie Th閞apeutique 1971,6(3),203-207
产品链接: CAS No. 32828-81-2››