FPP-028
4-乙基-2-苯基吡唑并[1,5-a]嘧啶-7(4H)-酮Chemical Name: 4-Ethyl-4,7-dihydro-2-phenylpyrazolo[1,5-a]pyrimidin-7-one
CAS No. 86969-15-5
项目整合开发状态: Preclinical
项目研究机构: Universit?degli Studi di Firenze (Originator)
合成路线:3-Phenyl-5-aminopyrazole (I) is reacted with sodium formylacetate (III) to give (II).Alkylation ot (II) with ethyl iodide (IV) in DMF solution in the presence ot K2CO3 gives the target compound.
📌 参考资料/链接：
参考文献标题:FPP-028
文献作者:Pirisino,R.; Messori,A.; Auzzi,G.; Bruni,F.; Pecori-Vettori,L.; Costanzo,A.; Cecchi,L.
参考来源:Drugs Fut 1987,12(4),345
📄 详细内容
合成路线:3-Phenyl-5-aminopyrazole (I) is reacted with sodium formylacetate (III) to give (II).Alkylation ot (II) with ethyl iodide (IV) in DMF solution in the presence ot K2CO3 gives the target compound.
参考文献标题:Further investigation on the antiinflammatory acti
文献作者:Pirisino,R.; Pecori-Vettori,L.; Ceppateli,P.; Corrias,M.; Mangano,G.; Ignesti,G.; Carla,V.
参考来源:Pharm Sci 1981,36682
合成路线:3-Phenyl-5-aminopyrazole (I) is reacted with sodium formylacetate (III) to give (II).Alkylation ot (II) with ethyl iodide (IV) in DMF solution in the presence ot K2CO3 gives the target compound.
参考文献标题:2-Phenylpirazolo[1-5-a]pyrimidin-7-ones.A new cla
文献作者:Auzzi,G.; Bruni,F.; Cecci,L.; Costanzo,A.; Pecori-Vettori,L.; Pirisino,R.; Corrias,M.; Ignesti,G.; Banchelli,G.; Raimondi,L.
参考来源:J Med Chem 1983,261706
产品链接: CAS No. 86969-15-5››