Apyramide, R025
4-(乙酰氨基)苯基 1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-乙酸酯Chemical Name: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
CAS No. 68483-33-0
项目整合开发状态: Phase II
项目研究机构: Marcel Richard (Originator)
合成路线:The esterification of indomethacin (I) with paracetamol (II) in the presence of DCC is performed in pyridine to afford apyramide,which is recrystallized in isopropanol.
📌 参考资料/链接:
参考文献标题:Apyramide
文献作者:Serrano,J.J.; Richard,M.; Sauvaire,D.; Michel,A.
参考来源:Drugs Fut 1987,12(3),203