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Brinzolamide CAS Registry Number: 138890-62-7 布林佐胺

CAS Name: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxideTrademarks: Azopt (Alcon)
Percent Composition: C 37.58%, H 5.52%, N 10.96%, O 20.86%, S 25.08%

📌 参考资料/链接：
Literature References: Carbonic anhydrase inhibitor. Prepn: T. R. Dean et al., WO 9115486; eidem, US 5378703 (1991, 1995 both to Alcon). Clinical trial: L. H. Silver, Am. J. Ophthalmol. 126, 400 (1998).

📄 详细内容

Properties: Sol in ethanol.
Derivative Type: Hydrochloride
CAS Registry Number: 150937-43-2
Percent Composition: C 34.32%, H 5.28%, N 10.01%, O 19.05%, S 22.91%, Cl 8.44%
Properties: Crystals from methanol + methylene chloride, mp 175-177°. [a]D +10.35° (c = 1 in water).
Melting point: mp 175-177°
Optical Rotation: [a]D +10.35° (c = 1 in water)
Therap-Cat: Antiglaucoma agent.
Keywords: Antiglaucoma; Carbonic Anhydrase Inhibitor.
产品链接: 138890-62-7››

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