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Perhexiline CAS Registry Number: 6621-47-2 哌克昔林

CAS Name: 2-(2,2-Dicyclohexylethyl)piperidine
Additional Names: 1,1-dicyclohexyl-2-(2-piperidyl)ethane; perhexilene
Percent Composition: C 82.24%, H 12.71%, N 5.05%

📌 参考资料/链接：
Literature References: Calcium blocking agent. Prepn: GB 1025578 (1966 to Richardson-Merrell), C.A. 65, 2229f (1966). Pharmacology: Hudak et al., J. Pharmacol. Exp. Ther. 173, 371 (1970). Clinical studies: Winsor, Clin. Pharmacol. Ther. 11, 85 (1970). Toxicity study: Causa, Perri, Arzneim.-Forsch. 21, 114 (1971). Series of articles: Postgrad. Med. J. Suppl. 49, 8-132 (1973). Book: Antiarrhythmic Action and the Puzzle of Perhexiline, E. M. Vaughan Williams, Ed. (Academic Press, New York, 1980) 143 pp.

📄 详细内容

Derivative Type: Maleate
CAS Registry Number: 6724-53-4
Trademarks: Pexid (Sigma)
Percent Composition: C 70.19%, H 9.99%, N 3.56%, O 16.26%
Properties: mp 188.5-191°. LD50 in rats, mice (g/kg): 7, 4.37 orally (Causa, Perri).
Melting point: mp 188.5-191°
Toxicity data: LD50 in rats, mice (g/kg): 7, 4.37 orally (Causa, Perri)
Derivative Type: Hydrochloride
Percent Composition: C 72.69%, H 11.56%, N 4.46%, Cl 11.29%
Properties: White crystalline powder, mp 243-245.5° (dec).
Melting point: mp 243-245.5° (dec)
Therap-Cat: Vasodilator (coronary); diuretic.
Keywords: Calcium Channel Blocker; Diuretic; Vasodilator (Coronary).
产品链接: 6621-47-2››

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