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Cinacalcet CAS Registry Number: 226256-56-0 西那卡塞

CAS Name: (aR)-a-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-napthalenemethanamine
Additional Names: (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylaminePercent Composition: C 73.93%, H 6.20%, F 15.95%, N 3.92%

📌 参考资料/链接：
Literature References: Calcimimetic. Prepn: B. C. Van Wagenen et al., US 6211244 (2001 to NPS Pharmaceuticals). Review of pharmacology and mechanism of action: M. Wada, N. Nagano, Nephrol. Dial. Transplant. 18, Suppl. 3, iii13-iii17 (2003); of clinical development: N. Franceschini et al., Expert Opin. Invest. Drugs 12, 1413-1421 (2003). Clinical trial in secondary hyperparathyroidism: G. A. Block et al., N. Engl. J. Med. 350, 1516 (2004).

📄 详细内容

Derivative Type: Hydrochloride
CAS Registry Number: 364782-34-3
Trademarks: Mimpara (Amgen); Sensipar (Amgen)
Percent Composition: C 67.09%, H 5.89%, F 14.47%, N 3.56%, Cl 9.00%
Properties: White to off-white, crystalline solid. Sol in methanol, 95% ethanol; slightly sol in water.
Therap-Cat: Antihyperparathyroid.
Keywords: Antihyperparathyroid.
产品链接: 226256-56-0››

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