Prucalopride CAS Registry Number: 179474-81-8 普芦卡必利
CAS Name: 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamideTrademarks: Resolor (J J)
Percent Composition: C 58.77%, H 7.12%, Cl 9.64%, N 11.42%, O 13.05%
📌 参考资料/链接：
Literature References: Benzofuran derivative; specific serotonin 5-HT4 receptor agonist. Prepn: G. H. P. Van Daele et al., WO 9616060; eidem, US 5854260 (1996, 1998 both to Janssen). Effect on isolated gastrointestinal muscle: N. H. Prins et al., Br. J. Pharmacol. 127, 1431 (1999). Clinical stimulation of colonic transit: E. P. Bouras et al., Gut 44, 682 (1999).
📄 详细内容
Properties: Monohydrate, mp 90.7°.
Melting point: mp 90.7°
Therap-Cat: Gastroprokinetic.
Keywords: Gastroprokinetic.
产品链接: 179474-81-8››