Metaclazepam CAS Registry Number: 84031-17-4 7-溴-5-(2-氯苯基)-2,3-二氢-2-(甲氧基甲基)-1-甲基-1H-1,4-苯并二氮杂卓
CAS Name: 7-Bromo-5-(2-chlorophenyl)-2,3-dihydro-2-(methoxymethyl)-1-methyl-1H-1,4-benzodiazepine
Additional Names: brometazepam; metuclazepamPercent Composition: C 54.91%, H 4.61%, Br 20.30%, Cl 9.00%, N 7.12%, O 4.06%
📌 参考资料/链接：
Literature References: Benzodiazepine deriv with alkoxymethyl group replacing carbonyl in parent compd. Prepn: W. Milkowski et al., DE 2221558; eidem, US 4098786 (1973, 1978 both to Kali-Chemie). Effect on psychomotor performance and memory in volunteers: Z. Subhan, I. Hindmarch, Drugs Exp. Clin. Res. 9, 567 (1983). Interaction with ethanol: H. R. Musch, M. Ruhland, Arzneim.-Forsch. 32, 567 (1982); H. J. Mallach et al., Blutalkohol 20, 196 (1983); V. Schmidt et al., Med. Welt 35, 32 (1984). Clinical studies: G. Laakman et al., Arzneim.-Forsch. 30, 1233 (1980).
📄 详细内容
Derivative Type: Hydrochloride
CAS Registry Number: 61802-93-5
Trademarks: Talis (Kali-Chemie)
Percent Composition: C 50.26%, H 4.45%, Br 18.57%, Cl 16.48%, N 6.51%, O 3.72%
Properties: Crystals from ethanol, mp 193-196°. LD50 orally in NMRI white mice: 1578 mg/kg (Milkowski).
Melting point: mp 193-196°
Toxicity data: LD50 orally in NMRI white mice: 1578 mg/kg (Milkowski)
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Benzodiazepine Derivatives.
产品链接: 84031-17-4››