Nucleocidin CAS Registry Number: 24751-69-7 核杀菌素
CAS Name: 4'-C-Fluoroadenosine 5'-sulfamate
Additional Names: 9-(4-fluoro-5-O-sulfamoylpentofuranosyl)adenine; 4'-fluoro-5'-O-sulfamoyladenosine
Percent Composition: C 32.97%, H 3.60%, F 5.21%, N 23.07%, O 26.35%, S 8.80%
📌 参考资料/链接：
Literature References: Antitrypanosomal antibiotic produced by Streptomyces calvus. The first naturally occurring derivative of a fluoro sugar. Isoln and activity studies: Thomas et al., Antibiot. Annu. 1956-1957, 716; Hewitt et al., ibid. 722. Partial structure: Waller et al., J. Am. Chem. Soc. 79, 1011 (1957). Revised formula and structure: Morton et al., ibid. 91, 1535 (1969). Synthesis: Jenkins et al., ibid. 93, 4323 (1971).
📄 详细内容
Properties: As the monohydrate, crystalline, weakly alkaline substance. mp 190° (dec). uv max (methanol): 259 nm (e 15000). LD50 i.p. in mice: ~0.2 mg/kg (Thomas).
Melting point: mp 190° (dec)
Absorption maximum: uv max (methanol): 259 nm (e 15000)
Toxicity data: LD50 i.p. in mice: ~0.2 mg/kg (Thomas)
产品链接: 24751-69-7››