Prednicarbate CAS Registry Number: 73771-04-7 泼尼卡酯
CAS Name: (11b)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
Additional Names: 11b,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-(ethyl carbonate) 21-propionate; prednisolone 17-ethylcarbonate 21-propionateTrademarks: Dermatop (HMR); Prednitop (BASF); Regenit (Hoechst)
Percent Composition: C 66.38%, H 7.43%, O 26.20%
📌 参考资料/链接：
Literature References: Topical anti-inflammatory agent. Prepn: U. Stache et al., DE 2735110; eidem, US 4242334 (1979, 1980 both to Hoechst AG); U. Stache et al., Arzneim.-Forsch. 35, 1753 (1985). Topical and systemic activity in rats: H. G. Alpermann et al., ibid. 32, 633 (1982). Series of articles on pharmacology, pharmacokinetics and clinical efficacy: Z. Hautkrankhr. 61, Suppl. 1, 1-96 (1986).
📄 详细内容
Properties: Crystals from ethanol + diethylether, mp 110-112°; second crystalline form, mp 183°. uv max (ethanol): 241 nm (e 15000). [a]D20 +63° (c = 0.1 in ethanol). Practically insol in water. Freely sol in ethanol.
Melting point: mp 110-112°; mp 183°
Optical Rotation: [a]D20 +63° (c = 0.1 in ethanol)
Absorption maximum: uv max (ethanol): 241 nm (e 15000)
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.
产品链接: 73771-04-7››