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Chlorbenzoxamine CAS Registry Number: 522-18-9 氯苄沙明

CAS Name: 1-[2-[(2-Chlorophenyl)phenylmethoxy]ethyl]-4-[(2-methylphenyl)methyl]piperazine
Additional Names: 1-[2-(o-chloro-a-phenylbenzyloxy)ethyl]-4-o-methylbenzylpiperazine; 1-[2'-(o-chlorobenzhydryloxy)ethyl]-4-(o-methylbenzyl)diethylenediamine; 1-(o-chlorobenzhydryloxyethyl)-4-(o-methylbenzyl)piperazine; chlorbenzoxyethamine; chlorobenzoxamine
Percent Composition: C 74.55%, H 7.18%, Cl 8.15%, N 6.44%, O 3.68%

📌 参考资料/链接：
Literature References: Anticholinergic. Prepn: Morren et al., Ind. Chim. Belge 22, 409 (1957); Morren, GB 837986 (1960). Toxicity study: Levis et al., Arch. Int. Pharmacodyn. Ther. 118, 167 (1959).

📄 详细内容

Properties: bp0.01 234-236°; bp0.005 235°.
Boiling point: bp0.01 234-236°; bp0.005 235°
Derivative Type: Dihydrochloride
CAS Registry Number: 5576-62-5Trademarks: Libratar (UCB); Gastomax (Brocchieri)
Percent Composition: C 63.85%, H 6.55%, Cl 20.94%, N 5.52%, O 3.15%
Properties: Bitter crystals, mp 197-200°. Freely sol in methanol; sol in ethanol, chloroform, acetic acid; slightly sol in water, acetone. Practically insol in acetonitrile, ether, benzene. LD50 in rats (mg/kg): 4000 s.c., 66 i.v.; in mice (mg/kg): 1400 orally (Levis).
Melting point: mp 197-200°
Toxicity data: LD50 in rats (mg/kg): 4000 s.c., 66 i.v.; in mice (mg/kg): 1400 orally (Levis)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.
产品链接: 522-18-9››

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