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Fosfestrol CAS Registry Number: 522-40-7 乙烯雌酚二磷酸酯

CAS Name: 4,4'-[(1E)-1,2-Diethyl-1,2-ethenediyl]bisphenol bis(dihydrogen phosphate)
Additional Names: a,a'-diethyl-4,4'-stilbenediol diphosphoric acid ester; diethylstilbestrol diphosphate; diethylstilbestryl diphosphate; diethyldihydroxystilbene diphosphate; stilbestrol diphosphate
Trademarks: Stilphostrol (Bayer)
Percent Composition: C 50.48%, H 5.18%, O 29.88%, P 14.46%

📌 参考资料/链接：
Literature References: Synthetic, nonsteroidal estrogen. Prepd by treating stilbestrol with phosphorus oxychloride in pyridine: Miescher, Heer, US 2234311 (1941); Arnold, US 2802854 (1957 to Asta-Werke). Prepn of stable solns at pH 10: Fonner, Collins, US 2828244 (1958 to Miles Labs.). Prepn of sodium salts: Dawson, US 2971975 (1961 to Miles Labs.). Clinical pharmacokinetics: H. Oelschläger et al., Arzneim.-Forsch. 36, 1284 (1986). Review of clinical trials in prostate cancer: J-P. Droz et al, Cancer 71, 1123-1130 (1993).

📄 详细内容

Properties: Voluminous white cryst powder from dil HCl. Dec 204-206°. Sparingly sol in water.
Derivative Type: Disodium salt
CAS Registry Number: 5965-09-3
Percent Composition: C 45.78%, H 4.27%, Na 9.74%, O 27.10%, P 13.12%
Properties: Crystals. Softens at 190°, uniform melt at 230°. Sol in water. pH of aq soln 6.5. pH also reported as 4.85 to 5.00.
Melting point: melt at 230°
Derivative Type: Tetrasodium salt
CAS Registry Number: 4719-75-9
Trademarks: Honvan (Baxter); Honvol (Horner); ST-52 (Baxter); Stilbostatin (Taro)
Percent Composition: C 41.88%, H 3.51%, Na 17.81%, O 24.79%, P 12.00%
Therap-Cat: Antineoplastic (hormonal).
Keywords: Antineoplastic (Hormonal); Estrogens; Estrogen; Nonsteroidal.
产品链接: 522-40-7››

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