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Vinconate CAS Registry Number: 70704-03-9 长春考酯

CAS Name: 3-Ethyl-2,3,3a,4-tetrahydro-1H-indolo[3,2,1-de][1,5]naphthyridine-6-carboxylic acid methyl ester
Additional Names: chanodesethylapovincamine
Percent Composition: C 72.95%, H 6.80%, N 9.45%, O 10.80%

📌 参考资料/链接：
Literature References: Synthetic hexahydrocanthane alkaloid; vincamine analog. Prepn: BE 870887; J. A. A. Hannart, US 4200638 (1979, 1980 both to Omnium Chim.). Pharmacology: K. Ninomiya et al., Iyakuhin Kenkyu 23, 620 (1992), C.A. 118, 32823 (1992). Pharmacokinetics: M. Kinbara, Y. Satou, ibid. 275, C.A. 117, 123938 (1992). Nootropic activity: H. Kinoshita et al., Res. Commun. Chem. Pathol. Pharmacol. 84, 175 (1994). Clinical pharmacology: B. Saletu et al., Arch. Gerontol. Geriatr. 3, 127 (1984). Acute toxicity study: N. Nishimura et al., Yakuri to Chiryo 20, Suppl. 8, S1995 (1992), C.A. 118, 52241 (1992).

📄 详细内容

Properties: mp 120-121°.
Melting point: mp 120-121°
Derivative Type: Monohydrochloride
CAS Registry Number: 119600-43-0Percent Composition: C 64.96%, H 6.36%, N 8.42%, O 9.61%, Cl 10.65%
Properties: mp 194-195°. LD50 in male, female mice, rats (mg/kg): 947, 699, 2582, 2348 orally; 127, 131, 112, 117 i.v.; 4073, 3446, 6000, 6000 s.c. (Nishimura).
Melting point: mp 194-195°
Toxicity data: LD50 in male, female mice, rats (mg/kg): 947, 699, 2582, 2348 orally; 127, 131, 112, 117 i.v.; 4073, 3446, 6000, 6000 s.c. (Nishimura)
Therap-Cat: Nootropic.
Keywords: Nootropic.
产品链接: 70704-03-9››

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