Gusperimus CAS Registry Number: 104317-84-2 胍立莫司

📌 参考资料/链接：
Literature References: Synthetic derivative of the antitumor antibiotic spergualin. Prepn: BE 894651; H. Umezawa et al., US 4518532 (1983, 1985 both to Microbiochem. Res. Found.); Y. Umeda et al., J. Antibiot. 38, 886 (1985). Prepn of the active (-)-isomer: H. Iwasawa et al., ibid. 35, 1665 (1982); H. Umezawa et al., EP 94632; eidem, US 4525299 (1983, 1985 both to Microbiochem. Res. Found.). Synthesis and bioactivity of isomers: Y. Umeda et al., J. Antibiot. 40, 1316 (1987). Mechanism of action study: W. E. G. Müller et al., ibid. 1028. HPLC determn in plasma: R. Nakanuma et al., J. Chromatogr. 527, 208 (1990). Pharmacokinetics: J. F. Muindi et al., Cancer Res. 51, 3096 (1991). Preliminary evaluation in renal transplant rejection: H. Amemiya et al., Transplant. Proc. 25, 730 (1993). Series of articles on synthesis and immunomodulating activity: Ann. N.Y. Acad. Sci. 685, 123-206 (1993).