Derivative Type: Bromide
CAS Registry Number: 114-80-7
Trademarks: Juvastigmin (tabl.) (Dolder); Neoesserin (Ankerpharm); Neostigmin (tabl.) (Ferrosan); Normastigmin (tabl.) (Sigmapharm); Prostigmin (Roche)
Percent Composition: C 47.54%, H 6.32%, Br 26.35%, N 9.24%, O 10.55%
Properties: Crystals from alcohol + ether, dec ~167°. One gram dissolves in ~1 ml water. Sol in alc.
Derivative Type: Methyl sulfate
CAS Registry Number: 51-60-5
Trademarks: Intrastigmina (Lusofarmaco); Juvastigmin (amp.) (Dolder); Metastigmin (Star); Neostigmin (inj.) (Ferrosan); Normastigmin (amp.) (Sigmapharm); Prostigmin (amp.) (Roche); Stiglyn (Mallinckrodt Vet.)
Percent Composition: C 46.69%, H 6.63%, N 8.38%, O 28.71%, S 9.59%
Properties: Crystals from alc, mp 142-145°. One gram dissolves in ~10 ml water, less sol in alcohol. LD50 in mice (mg/kg): 0.16 i.v.; 0.42 s.c.; 7.5 orally, (Randall, Lehmann).
Melting point: mp 142-145°
Toxicity data: LD50 in mice (mg/kg): 0.16 i.v.; 0.42 s.c.; 7.5 orally, (Randall, Lehmann)
Therap-Cat: Cholinergic; miotic; antidote (curare).
Therap-Cat-Vet: Cholinergic; antidote (curare).
Keywords: Antidote (Curare); Cholinergic; Miotic.
产品链接: 59-99-4››