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Naratriptan CAS Registry Number: 121679-13-8 那拉曲坦

CAS Name: N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide
Percent Composition: C 60.87%, H 7.51%, N 12.53%, O 9.54%, S 9.56%

📌 参考资料/链接：
Literature References: Serotonin 5-HT1B/1D receptor agonist. Prepn: A. W. Oxford et al., EP 303507; eidem, US 4997841 (1989, 1991 both to Glaxo). Pharmacology and receptor binding study: H. E. Connor et al., Cephalalgia 17, 145 (1997). Determn in plasma and pharmacokinetics in rabbits: B. D. Duléry et al., J. Pharm. Biomed. Anal. 15, 1009 (1997). Clinical trial in migraine: H. Havanka et al., Clin. Ther. 22, 970 (2000).

📄 详细内容

Properties: Crystals from ethyl acetate, mp 170-171°.
Melting point: mp 170-171°
Derivative Type: Hydrochloride
CAS Registry Number: 143388-64-1Trademarks: Amerge (GSK); Naramig (GSK)
Percent Composition: C 54.90%, H 7.05%, N 11.30%, O 8.60%, S 8.62%, Cl 9.53%
Properties: Microcrystals, mp 237-239°.
Melting point: mp 237-239°
Therap-Cat: Antimigraine.
Keywords: Antimigraine; Serotonin Receptor Agonist.
产品链接: 121679-13-8››

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