Properties: Yellow-orange crystals, mp 300° (dec 140°). [a]D20 -4° (methanol). uv max (phosphate buffer soln pH 7.3): 223, 314, 445 nm (E1%1cm 586, 322, 204). Acid reaction. Slightly sol in water, petr ether; sol in ether, bicarbonate soln; very sol in methanol, ethanol, acetone, ethyl acetate. A reducing substitute, such as ascorbic acid, should be added to aq solns of rifamycin SV to prevent its transformation to rifamycin S. LD50 in mice (mg/kg): 550 i.v.; 625 i.p.; 2120 orally (Bergamini, Fowst).
Melting point: mp 300° (dec 140°)
Optical Rotation: [a]D20 -4° (methanol)
Absorption maximum: uv max (phosphate buffer soln pH 7.3): 223, 314, 445 nm (E1%1cm 586, 322, 204)
Toxicity data: LD50 in mice (mg/kg): 550 i.v.; 625 i.p.; 2120 orally (Bergamini, Fowst)
Derivative Type: Sodium salt
CAS Registry Number: 14897-39-3
Trademarks: Rifamastene (Uce); Rifocin (Lepetit)
Properties: Orange-red crystals. Soly in water pH 7.2: ~5 g/100 ml.
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Antibiotics); Ansamycins.
产品链接: 6998-60-3››