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Floxacillin CAS Registry Number: 5250-39-5 氟氯西林

CAS Name: (2S,5R,6R)-6-[[[3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Additional Names: 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin; 6-[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamido]penicillanic acid; flucloxacillinPercent Composition: C 50.28%, H 3.78%, Cl 7.81%, F 4.19%, N 9.26%, O 17.63%, S 7.06%

📌 参考资料/链接：
Literature References: Semi-synthetic antibiotic active against penicillin-resistant staphylococci. Halogen-substituted derivative of oxacillin, q.v. Prepn: ZA 6304323 (1964 to Beecham); Nayler, GB 978299; idem, US 3239507 (1964, 1966 both to Beecham). Pharmacology and toxicity: R. Sutherland et al., Br. Med. J. 4, 460 (1970). Clinical studies: Harding et al., Clin. Trials J. 7, 368 (1970); Qureshi et al., ibid. 375.

📄 详细内容

Derivative Type: Sodium monohydrate
CAS Registry Number: 34214-51-2
Trademarks: Abboflox (Abbott); Culpen (Fujisawa); Floxapen (GSK); Ladropen (Berk); Stafoxil (Yamanouchi); Staphlipen (Wyeth); Staphylex (GSK)
Percent Composition: C 46.21%, H 3.67%, Cl 7.18%, F 3.85%, N 8.51%, Na 4.66%, O 19.44%, S 6.49%
Properties: Freely sol in water. LD50 in mice (g/kg): 2.2 s.c., 3.8 orally (Sutherland).
Toxicity data: LD50 in mice (g/kg): 2.2 s.c., 3.8 orally (Sutherland)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.
产品链接: 5250-39-5››

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