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Piromidic Acid CAS Registry Number: 19562-30-2 吡乙酸三氮萘

CAS Name: 8-Ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid
Additional Names: 5,8-dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido[2,3-d]pyrimidine-6-carboxylic acidTrademarks: Bactramyl (Carrion); Enterol (Lenza); Gastrurol (Gibipharma); Panacid (Dainippon); Pirodal (SIT); Purim (Laphal); Reelon (Sanwa); Septural (Grñenthal); Uropir (Sarm)
Percent Composition: C 58.32%, H 5.59%, N 19.43%, O 16.65%

📌 参考资料/链接：
Literature References: Quinolone antibacterial. Prepn: S. Minami et al., JP 67 25912; eidem, GB 1129358 (1967, 1968 both to Dainippon Pharm.); eidem, Chem. Pharm. Bull. 19, 1426 (1971). Activity studies: M. Shimizu et al., Antimicrob. Agents Chemother. 1970, 117. Metabolism: eidem, ibid. 123.

📄 详细内容

Properties: Crystals from ethanol-chloroform, mp 314-316°. LD50 in male, female mice, male, female rats (mg/kg): 287, 268, 177, 158 i.v.; all 4000 orally, s.c. and i.p. (Shimizu).
Melting point: mp 314-316°
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 287, 268, 177, 158 i.v.; all 4000 orally, s.c. and i.p. (Shimizu)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.
产品链接: 19562-30-2››

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