Otilonium Bromide CAS Registry Number: 26095-59-0 奥替溴铵

📌 参考资料/链接：
Literature References: Quaternary ammonium salt with gastrointestinal spasmolytic activity. Prepn: BE 704269; M. Ghelardoni et al., US 3536723 (1968, 1970 both to Menarini); idem et al., J. Med. Chem. 16, 1063 (1973). Determn of finished pharmaceutical forms by HPLC: C. Mannucci et al., J. Pharm. Sci. 82, 367 (1993); by CE: S. Furlanetto et al., Analyst 126, 1700 (2001). Receptor binding study: S. Lindqvust et al., Br. J. Pharmacol. 137, 1134 (2002). Clinical trial in irritable bowel syndrome: G. Battaglia et al., Aliment. Pharmacol. Ther. 12, 1003 (1998). Review of pharmacology and clinical efficacy: S. Evangelista, J. Int. Med. Res. 27, 207-222 (1999); comparative review of clinical studies: idem, Curr. Pharm. Des. 10, 3561-3568 (2004).