Derivative Type: Sodium salt
CAS Registry Number: 730-68-7
Additional Names: MethioturiateTrademarks: Neraval (Schering); Thiogenal
Percent Composition: C 46.43%, H 6.17%, N 9.02%, Na 7.41%, O 10.31%, S 20.66%
Properties: Very hygroscopic, yellow crystals. Slight odor of mercaptans. Freely sol in water. pH of a 10% aq soln ~9.5. Water solns are unstable as evidenced by a deepening of color and formation of a cloudy precipitate upon autoclaving and exposure to light. The addition of sodium carbonate has a stabilizing effect and prevents precipitation for about 24 hrs: Irwin et al., J. Pharmacol. Exp. Ther.
116, 317 (1956).
NOTE: This is a controlled substance (depressant):
21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
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