Properties: Amphoteric, amorphous base. [a]D24 +126.6° (c = 0.5 in chloroform). uv max (0.01N alcoholic H2SO4): 240, 310 nm (E1%1cm 183.7, 80.6). Soluble in acidic or strongly basic aq solns, practically insol in the pH range of 7 to 10. Soluble in the more polar organic solvents, but not in ether or light hydrocarbons. Active against gram-positive organisms and plant pathogens such as B. stewartii, P. fascians, X. pruni at 0.5 g/ml. The antibacterial activity is rapidly destroyed in aq solns above pH 9 at 24°, but remains at pH 5 to 7 for at least 60 days. Celesticetin is more stable in acid than in basic solns, but is destroyed rapidly in 1N HCl at 100°. Cross resistance with erythromycin.
Optical Rotation: [a]D24 +126.6° (c = 0.5 in chloroform)
Absorption maximum: uv max (0.01N alcoholic H2SO4): 240, 310 nm (E1%1cm 183.7, 80.6)
Derivative Type: Salicylate
Properties: Monoclinic tablets, mp 139°. [a]D24 +90.2° (c = 0.5 in H2O). Sol in water.
Melting point: mp 139°
Optical Rotation: [a]D24 +90.2° (c = 0.5 in H2O)
Derivative Type: Oxalate
Properties: Crystals, mp 149-154°. [a]D24 +106.6° (c = 0.5 in H2O). Sol in water.
Melting point: mp 149-154°
Optical Rotation: [a]D24 +106.6° (c = 0.5 in H2O)
产品链接: 2520-21-0››