Properties: Crystals from ethyl acetate, mp 231-234° (dec). [a]D +108° (acetone). uv max (methanol): 238 nm (e 15200).
Melting point: mp 231-234° (dec)
Optical Rotation: [a]D +108° (acetone)
Absorption maximum: uv max (methanol): 238 nm (e 15200)
Derivative Type: 21-Acetate
CAS Registry Number: 987-24-6
Trademarks: Betafluorene (Lepetit); Celestovet (Biokema)
Percent Composition: C 66.34%, H 7.19%, F 4.37%, O 22.09%
Properties: Hexagonal prisms from acetone + ether, mp 205-208° (Taub); also reported as mp 196-201° (Oliveto). [a]D +140° (chloroform). uv max (methanol): 238 nm (e 14800).
Melting point: mp 205-208° (Taub); mp 196-201° (Oliveto)
Optical Rotation: [a]D +140° (chloroform)
Absorption maximum: uv max (methanol): 238 nm (e 14800)
Derivative Type: 17-Benzoate
CAS Registry Number: 22298-29-9Trademarks: Bebate; Beben (Pfizer); Benisone (Warner-Chilcott); Euvaderm (Gecke); Flurobate (Texas Pharmacal); Uticort (Pfizer)
Percent Composition: C 70.14%, H 6.70%, F 3.83%, O 19.33%
Properties: Crystals from acetone-ether, mp 225-228°. [a]D24 +63.5° (dioxane). Synthesis and activity: Ercoli et al., J. Med. Chem.
15, 783 (1972). See also Cullen, Curr. Ther. Res.
15, 243 (1973).
Melting point: mp 225-228°
Optical Rotation: [a]D24 +63.5° (dioxane)
Derivative Type: 17,21-Dipropionate
CAS Registry Number: 5593-20-4Trademarks: Diproderm (Schering-Plough); Diprolene (Schering-Plough); Diprophos (Schering-Plough); Diprosis (Essex); Diprosone (Schering-Plough); Maxivate (Westwood); Rinderon-DP (Shionogi)
Percent Composition: C 66.65%, H 7.39%, F 3.77%, O 22.20%
Properties: Powder, mp 170-179° (dec). [a]D26 +65.7° (dioxane). uv max (methanol): 238 nm (e 15700). Insol in water.
Melting point: mp 170-179° (dec)
Optical Rotation: [a]D26 +65.7° (dioxane)
Absorption maximum: uv max (methanol): 238 nm (e 15700)
Derivative Type: 17-Valerate
CAS Registry Number: 2152-44-5
Trademarks: Bedermin (Damor); Betnesol-V (GSK); Betneval (GSK); Betnovate (GSK); Bextasol (GSK); Celestan-V (Essex); Celestoderm-V (Schering-Plough); Dermosol (Iwaki); Dermovaleas (Valeas); Ecoval 70; Hormezon (Tobishi); Tokuderm (Nichiban); Valisone (Schering-Plough)
Percent Composition: C 68.05%, H 7.83%, F 3.99%, O 20.14%
Properties: Needles from acetone + petr ether, mp 183-184°. [a]D +77° (dioxane). uv max: 239 nm (e 15920).
NL
6406615 (1964 to Glaxo).
Melting point: mp 183-184°
Optical Rotation: [a]D +77° (dioxane)
Absorption maximum: uv max: 239 nm (e 15920)
Derivative Type: 21-Phosphate disodium salt
CAS Registry Number: 151-73-5
Additional Names: Betamethasone 21-(dihydrogen phosphate) disodium salt
Trademarks: Bentelan (GSK); Betnesol (GSK); Celestan (Essex); Durabetason (Durachemie); Vista-Methasone (Richard Daniel)
Percent Composition: C 51.17%, H 5.47%, F 3.68%, Na 8.90%, O 24.79%, P 6.00%
Therap-Cat: Glucocorticoid.
Therap-Cat-Vet: Glucocorticoid.
Keywords: Glucocorticoid.
产品链接: 378-44-9››