Nafronyl CAS Registry Number: 31329-57-4 萘呋胺酯
CAS Name: Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic acid 2-(diethylamino)ethyl ester
Additional Names: tetrahydro-a-(1-naphthylmethyl)-2-furanpropionic acid 2-(diethylamino)ethyl ester; 3-(1-naphthyl)-2-tetrahydrofurfurylpropionic acid 2-(diethylamino)ethyl ester; a-tetrahydrofurfuryl-1-naphthalenepropionic acid 2-(diethylamino)ethyl ester; N-diethylaminoethyl b-(1-naphthyl)-b-tetrahydrofuryl isobutyrate; naftidrofuryl
Trademarks: Dubimax (Oberval); Gevatran (Anphar-Rolland)
Percent Composition: C 75.16%, H 8.67%, N 3.65%, O 12.52%
📌 参考资料/链接：
Literature References: Prepn: Szarvasi, Bayssat, FR 1363948 corresp to US 3334096 (1964, 1967 both to LIPHA); Szarvasi et al., Compt. Rend. 260, 3095 (1965); eidem, Bull. Soc. Chim. Fr. 1966, 1838. Activity studies: Fontaine et al., C.R. Seances Acad. Sci. Ser. D 262, 719 (1966). Metabolism and toxicology: Fontaine et al., Chim. Ther. 4, 44 (1969); Fontaine et al., J. Eur. Toxicol. 11, 40 (1969). Acute toxicity: P. Bessin et al., Eur. J. Med. Chem. 10, 291 (1975). Clinical studies: C. A. Clyne et al., Br. J. Surg. 67, 347 (1980); R. M. Greenhalgh, ibid. 68, 265 (1981).
📄 详细内容
Properties: bp0.5 190°. d431 1.0465. nD29 1.5513. LD50 in mice (mg/kg): 365 orally (Bessin).
Boiling point: bp0.5 190°
Index of refraction: nD29 1.5513
Density: d431 1.0465
Toxicity data: LD50 in mice (mg/kg): 365 orally (Bessin)
Derivative Type: Acid oxalate
CAS Registry Number: 3200-06-4Trademarks: Citoxid (Disprovent); Di-Actane (Menarini); Dusodril (Roland); Praxilene (Lipha)
Percent Composition: C 65.94%, H 7.45%, N 2.96%, O 23.65%
Properties: Crystals from ethyl acetate, mp 110-111°. Slightly hygroscopic, sol in water.
Melting point: mp 110-111°
Therap-Cat: Vasodilator.
Keywords: Vasodilator (Cerebral); Vasodilator (Peripheral).
产品链接: 31329-57-4››