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Dibromopropamidine CAS Registry Number: 496-00-4 双溴丙脒

CAS Name: 4,4'-[1,3-Propanediylbis(oxy)]bis(3-bromobenzenecarboximidamide)
Additional Names: 4,4'-(trimethylenedioxy)bis(3-bromobenzamidine); 2',2''-dibromo-4',4''-diamidino-1,3-diphenoxypropane
Percent Composition: C 43.43%, H 3.86%, Br 33.99%, N 11.92%, O 6.81%

📌 参考资料/链接：
Literature References: Prepn: S. S. Berg, G. Newbery, GB 598911 (1948 to May Baker); eidem, J. Chem. Soc. 1949, 642. Antibacterial activity: R. Wien et al., Lancet 254, 711 (1948); A. D. Russell, J. R. Furr, Int. J. Pharm. 34, 115 (1986). Mode of action: W. Woodside, Microbios 8, 23 (1973). Clinical use in Acanthamoeba keratitis: J. J. Wiens, W. B. Jackson, Can. J. Ophthalmol. 23, 107 (1988). HPLC determn in cosmetics: B. Wyhowski de Bukanski, M. O. Masse, Int. J. Cosmet. Sci. 6, 283 (1984).

📄 详细内容

Derivative Type: Isethionate
CAS Registry Number: 614-87-9
Trademarks: Brolene Ointment (RPR); Brulidine (M B)
Percent Composition: C 34.91%, H 4.19%, Br 22.12%, N 7.76%, O 22.15%, S 8.88%
Properties: Prismatic needles from ethanol, mp 226°. Freely sol in water. One gram dissolves in 2 ml of water at 20°, in 60 g of 95% alcohol at 20°. Sol in glycerol. Practically insol in ether, chloroform, fixed oils, liquid petrolatum. Aq solns are very slightly acidic. Solns may be sterilized by heating at 100° for 30 min, but they should not be stored for more than a few days, and then only in neutral glass containers since some hydrolysis occurs with the formation of sparingly sol urea derivs. Incompat. with chlorides, sulfates, and many organic anions, all of which form sparingly sol salts.
Melting point: mp 226°
Use: Preservative in cosmetics.
Therap-Cat: Antiseptic; antiamebic.
Therap-Cat-Vet: Antiseptic, antimicrobial.
Keywords: Antiamebic; Antiseptic/Disinfectant.
产品链接: 496-00-4››

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