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Oxaflumazine CAS Registry Number: 16498-21-8 奥沙氟嗪

CAS Name: 10-[3-[4-[2-(1,3-Dioxan-2-yl)ethyl]-1-piperazinyl]propyl]-2-(trifluoromethyl)-10H-phenothiazine
Percent Composition: C 61.52%, H 6.35%, F 11.23%, N 8.28%, O 6.30%, S 6.32%

📌 参考资料/链接：
Literature References: Prepn: Ratouis, Boissier, Bull. Soc. Chim. Fr. 1966, 2963; eidem, DE 1911719 (1969 to S.I.F.A.), C.A. 72, 55480y (1970). Pharmacology: Boissier, Dumont, Therapie 26, 481 (1971). Metabolism: Boissier et al., Ann. Pharm. Fr. 30, 851 (1972). Clinical studies: Deniker et al., Therapie 26, 227 (1971).

📄 详细内容

Derivative Type: Disuccinate
CAS Registry Number: 7450-97-7Trademarks: Oxaflumine (Diamant)
Percent Composition: C 54.90%, H 5.96%, F 7.66%, N 5.65%, O 21.51%, S 4.31%
Properties: Crystals from acetonitrile, mp 136-138°. uv max (methanol): 259, 310 nm (log e 4.53, 3.58). LD50 in mice (mg/kg): 94 i.v.; 175 i.p.; 919 orally (Boissier, Dumont).
Melting point: mp 136-138°
Absorption maximum: uv max (methanol): 259, 310 nm (log e 4.53, 3.58)
Toxicity data: LD50 in mice (mg/kg): 94 i.v.; 175 i.p.; 919 orally (Boissier, Dumont)
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Phenothiazines.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 16498-21-8››

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