Picotamide CAS Registry Number: 32828-81-2 4-甲氧基-N,N'-二(3-吡啶甲基)-1,3-苯二甲酰胺
CAS Name: 4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide
Additional Names: 4-methoxy-N,N'-bis(3-pyridylmethyl)isophthalamide; N,N'-bis(3-picolyl)-4-methoxyisophthalamidePercent Composition: C 67.01%, H 5.36%, N 14.88%, O 12.75%
📌 参考资料/链接：
Literature References: Prepn: R. Selleri et al., Chim. Ther. 6, 203 (1971); G. Orzalesi, R. Selleri, FR 2100850 C.A. 77, 164502f (1972); prepn and use as inhibitor of blood platelet aggregation: eidem, US 3973026 (1972, 1976 both to Soc. Italo-Brit. L. Manetti-H. Roberts). Crystal structure of monohydrate: E. Foresti et al., Acta Crystallogr. C42, 220 (1986). Mechanism of action study: M. Berrettini et al., Boll. Soc. Ital. Biol. Sper. 59, 309 (1983). Clinical studies: R. Schmutzler et al., Age Ageing 7, 246 (1978); V. Coto et al., Minerva Cardioangiol. 34, 601 (1986).
📄 详细内容
Properties: Crystalline powder from benzene, mp 124°. LD50 i.p. in male mice: 1205 mg/kg (Orzalesi, Selleri, 1976).
Melting point: mp 124°
Toxicity data: LD50 i.p. in male mice: 1205 mg/kg (Orzalesi, Selleri, 1976)
Derivative Type: Monohydrate
CAS Registry Number: 80530-63-8
Trademarks: Plactidil (Novartis)
Percent Composition: C 63.95%, H 5.62%, N 14.20%, O 16.23%
Therap-Cat: Antithrombotic; fibrinolytic; anticoagulant.
Keywords: Anticoagulant; Antithrombotic.
产品链接: 32828-81-2››