Properties: Crystals from petr ether, mp 75-76°. [a]D25 -68.2° (c = 0.6 in chloroform).
Melting point: mp 75-76°
Optical Rotation: [a]D25 -68.2° (c = 0.6 in chloroform)
Derivative Type: Hydrochloride
CAS Registry Number: 1596-70-9
Percent Composition: C 70.29%, H 8.04%, N 3.73%, O 8.51%, Cl 9.43%
Properties: Crystals from methanol + ethyl acetate, mp 163-164°. [a]D25 -60.1° (c = 0.7).
Melting point: mp 163-164°
Optical Rotation: [a]D25 -60.1° (c = 0.7)
Derivative Type: 2-Naphthalenesulfonate
CAS Registry Number: 5714-90-9
Additional Names: Levopropoxyphene napsylate
Trademarks: Novrad (Lilly); Letusin; Contratuss
Percent Composition: C 70.17%, H 6.81%, N 2.56%, O 14.61%, S 5.85%
Properties: LD50 orally in female rats: 1455 ±77 mg/kg (Goldenthal).
Toxicity data: LD50 orally in female rats: 1455 ±77 mg/kg (Goldenthal)
Therap-Cat: Antitussive.
Keywords: Antitussive.
Percent Composition: C 77.49%, H 9.05%, O 13.46%
Literature References: Prepn: K. Miescher, C. Scholz,
US
2233025 (1941 to Ciba). Comprehensive description: K. Florey, Anal. Profiles Drug Subs.
4, 192-208 (1975).
Properties: Crystals, mp 144-145°.
Melting point: mp 144-145°
CAUTION: These substances are listed as known human carcinogens: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-115.
Therap-Cat: Estrogen.
Therap-Cat-Vet: Estrogen.
Keywords: Estrogen; Steroidal.
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