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Prednylidene CAS Registry Number: 599-33-7 泼尼立定


CAS Name: (11b)-11,17,21-Trihydroxy-16-methylenepregna-1,4-diene-3,20-dione
Additional Names: D1,4-pregnadiene-16-methylene-11b,17a,21-triol-3,20-dione; 16-methylene-11b,17a,21-trihydroxypregna-1,4-diene-3,20-dione; 16-methyleneprednisolone
Trademarks: Dacortilen (Merck KGaA); Decortilen (Merck KGaA)
Percent Composition: C 70.95%, H 7.58%, O 21.48%
📌 参考资料/链接:
Literature References: Prepn: Mannhardt et al., Tetrahedron Lett. no. 16, 21 (1960). Prepn of the 21-diethylaminoacetate: idem et al., DE 1134074 (1962 to E. Merck), C.A. 58, 568a (1963).

📄 详细内容


Properties: Solid, mp 233-235°. [a]D23 +31° (dioxane). uv max: 243 nm (e 15900).
Melting point: mp 233-235°
Optical Rotation: [a]D23 +31° (dioxane)
Absorption maximum: uv max: 243 nm (e 15900)
Derivative Type: 21-Diethylaminoacetate hydrochloride
CAS Registry Number: 22887-42-9
Trademarks: Decortilen soluble (Merck KGaA)
Percent Composition: C 64.42%, H 7.72%, N 2.68%, O 18.39%, Cl 6.79%
Properties: Solid, mp 245-246°. [a]D +45° (water). uv max (water): 246-247 nm (E1%1cm 300).
Melting point: mp 245-246°
Optical Rotation: [a]D +45° (water)
Absorption maximum: uv max (water): 246-247 nm (E1%1cm 300)
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.
产品链接: 599-33-7››