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Carpipramine CAS Registry Number: 5942-95-0 卡匹帕明

CAS Name: 1'-[3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-[1,4'-bipiperidine]-4'-carboxamide
Additional Names: 5-[3-(4-piperidino-4-carbamoylpiperidino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine; carbadipimidinePercent Composition: C 75.30%, H 8.58%, N 12.54%, O 3.58%

📌 参考资料/链接：
Literature References: Prepn: M. Nakanishi, T. Munakata, JP 66 6752; GB 1017986; Nakanishi et al., US 3329683 (1966, 1966, 1967 all to Yoshitomi); Nakanishi et al., J. Med. Chem. 13, 644 (1970). Pharmacology: Nakanishi et al., Arzneim.-Forsch. 18, 1435 (1968). Metabolism: Nakanishi et al., J. Pharm. Soc. Jpn. 90, 204 (1970).

📄 详细内容

Derivative Type: Dihydrochloride monohydrate
CAS Registry Number: 7075-03-8
Trademarks: Defekton (Yoshitomi); Prazinil (Specia)
Percent Composition: C 62.56%, H 7.88%, N 10.42%, O 5.95%, Cl 13.19%
Properties: Crystals from 90% methanol, mp 260°. Sparingly sol in water. LD50 in mice, rats (mg/kg): 28.2, 37.0 i.v.; 136.0, 76.0 i.p.; 2180, 1025 orally (Nakanishi, 1968).
Melting point: mp 260°
Toxicity data: LD50 in mice, rats (mg/kg): 28.2, 37.0 i.v.; 136.0, 76.0 i.p.; 2180, 1025 orally (Nakanishi, 1968)
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Other Tricyclics.
产品链接: 5942-95-0››

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