Viloxazine CAS Registry Number: 46817-91-8 维洛沙秦
CAS Name: 2-[(2-Ethoxyphenoxy)methyl]morpholine
Additional Names: 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazinePercent Composition: C 65.80%, H 8.07%, N 5.90%, O 20.23%
📌 参考资料/链接：
Literature References: Prepn: K. B. Mallion et al., GB 1138405; eidem, US 3714161 (1969, 1973 both to I.C.I.). Manufacturing process: S. A. Lee, GB 1260886; idem, US 3712890 (1972, 1973 both to I.C.I.). Pharmacology: Mallion et al., Nature 238, 157 (1972); Bereen, Lancet 1, 379 (1973). Toxicity: R. D. Brosnan et al., J. Int. Med. Res. 4, 83 (1976). Clinical evaluation in narcolepsy: C. Guilleminault et al., Sleep 9, 275 (1986). Review of pharmacology and therapeutic efficacy: R. M. Pinder et al., Drugs 13, 401 (1977).
📄 详细内容
Derivative Type: Hydrochloride
CAS Registry Number: 35604-67-2
Trademarks: Vivalan (Zeneca); Vicilan (Zeneca); Vivarint (Zeneca)
Percent Composition: C 57.04%, H 7.36%, N 5.12%, O 17.53%, Cl 12.95%
Properties: mp 185-186°. LD50 in mice (mg/kg): 1000 orally, 60 i.v. (Brosnan).
Melting point: mp 185-186°
Toxicity data: LD50 in mice (mg/kg): 1000 orally, 60 i.v. (Brosnan)
Therap-Cat: Antidepressant.
Keywords: Antidepressant.
产品链接: 46817-91-8››