网站主页>>>项目整合精选>>>项目整合精选>>>Nicoclonate CAS Registry Number: 10571-59-2 尼可氯酯

Nicoclonate CAS Registry Number: 10571-59-2 尼可氯酯

CAS Name: 3-Pyridinecarboxylic acid 1-(4-chlorophenyl)-2-methylpropyl ester
Additional Names: nicotinic acid p-chloro-a-isopropylbenzyl ester; 1-(p-chlorophenyl)isobutyl nicotinate; p-chlorophenylisopropylcarbinol nicotinate; 1-(p-chlorophenyl)-1-(nicotinoyloxy)-2-methylpropaneTrademarks: Lipidium (Rhone-Poulenc)
Percent Composition: C 66.32%, H 5.57%, Cl 12.24%, N 4.83%, O 11.04%

📌 参考资料/链接：
Literature References: Prepn: J. Nordmann, H. B. Swierkot, FR M3454; eidem, US 3367939 (1965, 1968 both to Kuhlmann).

📄 详细内容

Properties: Base, white needles from methanol and water, mp 61-62° (Maquenne block); 55-56.5° (Culatti block). Very soluble in lipids; sol in alcohols, benzene, toluene, ether and acetone. Practically insol in water.
Melting point: mp 61-62° (Maquenne block); 55-56.5° (Culatti block)
Derivative Type: Hydrochloride
Percent Composition: C 58.91%, H 5.25%, Cl 21.74%, N 4.29%, O 9.81%
Properties: Crystals from methanol, mp 124-127℃. LD50 i.p. in mice: 2.27 g/kg (Nordmann, Swierkot).
Melting point: mp 124-127℃
Toxicity data: LD50 i.p. in mice: 2.27 g/kg (Nordmann, Swierkot)
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Nicotinic Acid Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 10571-59-2››

← 返回产品列表